Promoting Pregnancy and Healthy Baby
Preimplantation Genetic Testing is a technique used to identify genetic defects in embryos created through IVF before it is implanted in the uterus. It allows for a healthy embryo to be selected for implantation, increasing the chances of conceiving and also having a healthy baby. The test is also recommended for couples with a genetic disorder, to eliminate any chances of passing it on to their child or the risk to their baby’s health.
The procedure involves Ovulation Induction to stimulate growth of eggs, followed by eggs retrieval, mixing of sperms and eggs to allow for fertilisation to create embryos and finally embryo(s) transfer into a woman’s womb.
There are four types of PGT tests:
PGT-A Analyses the number of chromosomes to identify abnormalities PGT-M Tests for inheritable genetic condition.
PGT-SR To identify any missing, extra or rearranged genetic material PGT-HLA Typing To help parents who have a child with life-threatening disorder and in need of bone marrow or cord blood transplant to identify another child with compatible protein or markers to help their sibling.
The procedure involves a biopsy of a small number of cells from each embryo to test for genetic disorders or to determine compatibility for HLA Typing.
Successfully Conceiving A Healthy Baby At An Older Age
The goal of PGT is essentially to increase the chances of a successful pregnancy by eliminating embryos with abnormalities, which causes difficulties conceiving and miscarriages. The risk of having children with genetic abnormalities increases with age and so PGT helps ensure a couple’s hope for a healthy baby.
PGT is recommended with:
- Older pregnancies (unless using donor eggs)
- Inheritable genetic disorder
- Recurrent IVF failures