HOPE After a Failed IVF

HOPE After a Failed IVF

“A failed IVF is an emotional roller coaster journey not only for a couple but for us, the fertility team as well. Just as much as a couple wishes to hear ‘it’s positive’ after an IVF procedure, the fertility team so wishes the same. A couple’s failure to conceive after an IVF is truly a big loss for us too”

Dr Navdeep Singh Pannu

A Failed IVF The Impact

Pictures of smiling parents and their new babies posted on social media feeds and magazine covers make in vitro fertilisation (IVF) look like a stroll in the park. But I know for a fact that only a couple who has gone through a failed IVF would truly understand how devastating it can be.

Denial – anger – bargaining – depression – acceptance. This is the grieving process a couple goes through after a failed IVF. The grieving they go through is somewhat similar to one who has lost a child.

“What if my IVF failed because I parked the car too far from my workplace and exert myself whilst walking?” or “Doctor, maybe you didn’t do enough for this IVF to be successful,” – the “what ifs” and blaming that ensues after a failed IVF can be endless.

And just as a couple grieves a failed IVF, a negative outcome is devastating for us, the fertility team too. My nurses, my embryologist and I – together, we put in our heart and soul to do everything possible in hopes of a successful IVF outcome for a couple. Unfortunately, sometimes it just doesn’t happen.

The average success rate of IVF globally is under 50 percent. This means that more than half of those who undergo IVF unfortunately do not get pregnant. A tough fact to digest, but it is the hard truth.

Coping Through Loss

After what seems like endless hormone injections, an egg extraction procedure, an embryo transfer and the waiting and praying for good news, a negative IVF result is profoundly depressing for a couple.

To a couple that has had a failed IVF, the first advice I give them is to take a break. I tell them to stop all medication and take as much time as they need to grieve and come to terms with the failure.

Some patients even go into deep mourning after a failed IVF, especially the woman for obvious reasons. To these couples, I advise them to seek the right help. I refer them to our Fertility Coach who helps them journey through the loss of a failed IVF which can be quite overwhelming and isolating.

Our Fertility Coach is truly a great help as she provides that extra mental and emotional support while assisting couples to navigate through their fertility struggles. Having struggled through infertility herself, she totally understands the journey of couples going through the same predicament.

The Next Step

I see failure as an opportunity to begin again – but more intelligently.

When an IVF fails, there can be a myriad of reasons. Usually, I will review a couple’s last IVF procedure to determine which areas could be improved to help boost the odds of success the next time around.

Depending on a couple’s situation, I may order additional tests such as Immune system tests, Hysteroscopy or Endometrial Receptivity Analysis (ERA) which could potentially help improve IVF success.

To better increase the odds of a positive outcome, I advise couples to change their diet plans and adopt a healthier lifestyle. In some cases, I even advise couples to try out Traditional Chinese Medicine (TCM). Yes, I believe in the benefits of TCM. Acupuncture which is part of TCM treatment has a calming effect on the body which helps make a person less anxious. A change in IVF protocol alongside this alternative medicine can sometimes do wonders.

Every couple is different and there is no one size that fits all. The path that is right will depend on a particular situation and what has already been tried by a couple before

There is HOPE

I always believe that a failure is not really a failure. It is success in progress. When you have had a failed IVF, don’t lose hope. It is not the end of the road to having that family you have always wanted. Seek the support that you need to get through this. Compassionate care is readily available at our facility for those coping and grieving through a failed IVF. You shouldn’t have to do this alone.

You are sure to have many questions. In addressing infertility, the sooner you have them answered, the better. Do list them down and call +6-03-80699333 (TMC Fertility & Women’s Specialist Centre, Puchong) or email ask@drnavdeepfertility.com to make an appointment to consult with Dr Navdeep.

A Story of HOPE - Joyce Simson’s Journey to Parenthood

A Story of HOPE

Joyce Simson’s Journey to Parenthood


“After taking that difficult step to see a Fertility Specialist, the first doctor we met told us that I would never ever get pregnant. That was the most heart-breaking news my husband and I had ever received in our journey to start a family.”

Joyce Simson

Trying to conceive – A truly trying time

I got married when I was 30. After unsuccessfully trying to conceive naturally for two years, we decided to see a Fertility Specialist. The very first doctor we met told us that we would never be able to conceive no matter what we did. It was devastating.

We did not give up. We kept trying.

Our journey to start a family was not an easy one. We went through numerous failed IVF cycles. Each failure got tougher than the previous one. I’d cry over the simplest of things – a song I heard on the radio on the way to work or the wine that I could suddenly consume since my IVF failed and I was not pregnant. I cried on All Souls’ Day grieving for that unborn child. I was almost broken. 

The most wonderful gift

After 12 years, four different Fertility Specialists, six cycles of IVF, countless numbers of self-injections and waiting through nail-biting 2-week-waits to find out if I was pregnant, today, we are a proud family of four – my husband, myself and my two boys. My eldest is now four and a half, and my youngest, is just two months old.

Having gone through this gut-wrenching and emotionally intense journey of trying for a child, my husband and I have the utmost gratitude to our Creator for giving us this miracle of life, an extension of ourselves.

My support system

It is important to have a strong support system. In my case, these came from my husband and my Fertility Specialist and his team.

My husband has been my strength. We kept our journey personal; so, we relied on each other for comfort and motivation. He was always there, supporting ‘us’ through the ups and downs.

My Fertility Specialist and his team were empathetic and professional. Dr Navdeep talked us through our options and risks and kept things real and grounded. The breadth and depth of his knowledge kept our hopes alive. For this, we are grateful.

Juggling between work and treatment was challenging. There were even times when I had to move my treatment due to work commitments.  It was tough to get full support from superiors as work was demanding and fertility cycles cannot be planned very much in advance. 

I urge those who are going through fertility treatments to find your support systems. The journey can be uncertain, and you will need all the support you can get.

Seek the right help

Having personally gone through the highs and lows of this whole journey changed me as a person. It brought about this strong desire in me to help others in the same boat. Today, I am a Fertility Coach, and my work is about helping couples to look deeper into themselves and process their emotions. It is my hope to see couples navigate through their struggles and move forward in their lives.

My advice to couples out there is to communicate with your spouse and collectively decide the next steps to take if you are going through infertility. Time is of the essence and what people say about your biological clock ticking is very real. Do your research and meet the right specialist for you.

Never give up because your victory could be right around the corner. Have faith to journey through infertility because with persistence and perseverance, you can realise your dreams.

My hope…

The do's and don't of IVF

体外人工受孕(IVF) 应当避免事项


The do's and don't of IVF

体外人工受孕(IVF) 应当注意事项


The do's and don't of IVF

ஐ.வி.எவ் – இன் செய்யக்கூடாதவை

ஐ.வி.எவ் – இன் செய்யக்கூடாதவை
வெளிச் சோதனை முறை கருக்கட்டல் (ஐ. வி. எவ்) சிகிச்சையின் முதல் கட்டம்– மருத்துவரின் ஆலோசனையை பின்பற்றுதல்.
பல காரணிகள் ஐ. வி. எவ் சிகிச்சையின் வெற்றியை குறைக்கலாம் , ஆனால் இதை நாம் எளிதாக தவிற்க்க முடியும்.
ஐ. வி.எவ் சிகிச்சையை கருதும் தம்பதியர்கள் செய்யக்கூடாத விசயங்களின் ஒரு பட்டியல் இங்கே உள்ளது. இதை தவிர்த்தால் ஐ. வி. எவ் சிகிச்சை சீராகவும் கர்பம் அடையும் சாத்தியம் அதிகரிக்கவும் கூடும்.
ஒரு ஆரோக்கியமான குடும்பத்தை சரியான விசயங்கள் அறிந்து தொடங்குங்கள். பின்வரும் இணைய இணைப்பில் மேலும் ஐ .வி. எவ் பற்றி கற்றுக்கொள்ளுங்கள்.



The do's and don't of IVF

ஐ வி எவ்-இன் செய்யக்கூடியவை

ஐ வி எவ்-இன் செய்யக்கூடியவை
வெளிச் சோதனை முறை கருக்கட்டல் (ஐ வி எவ்) சிகிச்சை மேற்கொள்ளவது தம்பதியர்கள் தேர்வு செய்யும் முக்கியமான வாழ்க்கை முடிவாகும்.
ஒரு குடும்பத்தைத் தொடங்குவதற்க்கான வாய்ப்பை ஒருவர் மிக கவனமாக எடுத்துக்கொள்ள வேண்டும். இப்படிச் செய்வதால் வெற்றிக்கரமாக கர்பமடையும் சாத்தியத்தை அதிகரிக்க முடியும்.
ஆனால், ஐ வி எவ் சிகிச்சை மேற்க்கொள்ளும் பொழுது கடைப்பிடிக்க வேண்டிய கவனமான வழிகளும் நடைமுறைகளும் என்ன?
இதனை பற்றி வருத்தம் படும் தம்பதியர்களுக்கு , ஐ வி எவ் சிகிச்சை சீராகவும் அதிகமான சாத்தியங்களுடன் நல்ல முடிவுகள் கிடைப்பதற்க்காகவும் செய்யக்கூடிய ஒரு பட்டியல் இங்கே உள்ளது.
ஒரு ஆரோக்கியமான குடும்பத்தை சரியான விசயங்கள் அறிந்து தொடங்குங்கள். பின்வரும் இணைய இணைப்பில் மேலும் ஐ வி எவ் பற்றி கற்றுக்கொள்ளுங்கள். : https://www.drnavdeepfertility.com/improving-the-odds/

The do's and don't of IVF

The Don’ts of IVF

Successful in-vitro fertilisation (IVF) starts with the basics – following the doctor’s advice.
A number of other factors may also impact the success of IVF,
and can quite easily be avoided.
For couples considering IVF, here’s a list of Don’ts to follow so your IVF procedure goes through smoothly and with a greater chance of achieving pregnancy.
Starting a healthy family in turn starts with the right knowledge.
Learn more about IVF by visiting the following link: https://www.drnavdeepfertility.com/improving-the-odds/

The do's and don't of IVF

The Do’s of IVF

Undergoing in-vitro fertilisation (IVF) is a major life decision for couples choosing to do so.
The chance of starting a family is one that should be taken with utmost care. In doing so, the potential for a successful pregnancy will improve.
But, just what are the careful steps and measures that should be adhered to when going through IVF?
For couples who are wondering, here’s a list of Do’s to follow so your IVF procedure goes through smoothly and with greater prospects for a positive outcome.
Starting a healthy family in turn starts with the right knowledge. Learn more about IVF by visiting the following link: https://www.drnavdeepfertility.com/improving-the-odds/

EmbryoGlue in Aiding Implantation

EmbryoGlue in Aiding Implantation

The Many Possibilities

"It is the little things that we do in combination that add up to become one big, happy success story," said Dr Navdeep when asked about the usage of EmbryoGlue in his IVF procedures. He added, "If one thing doesn't work and there is a possibility that something else might, then why not, especially if it is for the benefit of making a couple’s dream of conceiving a child come true."

The IVF process is often a journey of hope for couples. For Dr. Navdeep, he is committed to ensuring that they are provided with significant medical procedures options. Considering the amount of effort put in by a couple, including the physical and emotional challenges they go through in the whole IVF process, Dr. Navdeep and team take every possible step to help couples achieve their goal of becoming proud parents.

With time and money being two of the most important considerations for a couple going through an IVF, add-ons such as EmbryoGlue, which helps increase chances of implantation, play a very important role in contributing to the success of an IVF. Knowledge is key and knowing such an option is available lets a couple be more prepared on what to expect at the end of the whole IVF journey.

Implantation after an Embryo Transfer

Embryo transfer is probably one of the highest points in an IVF process for most people. It is the last step before the two-week wait period begins, before one knows if the transferred embryo has implanted and hopefully hears those magical words of “Congratulations, you’re pregnant.”

So, what really happens inside the womb after an embryo transfer? After this procedure, the embryo is expected to naturally implant itself in the womb. The embryo moves around the womb before stabilising at one point. A chemical reaction occurs between the embryo cells and the womb lining where the embryo embeds itself into the womb lining. All conditions need to be perfect here, where the inner lining of the womb and embryo have to be in sync. This is when the embryo attaches to the endometrial blood supply and a person eventually becomes pregnant. At this point, the hormone progesterone enriches the uterus lining and helps sustain the growing embryo.

Implantation, however, may not always occur naturally as expected. There could be a number of factors affecting implantation of the embryo. This includes unhealthy embryos where an embryo looks good in the lab but may have defects, causing it to stop growing. Apart from that, unreceptive womb lining is another reason why implantation may not occur where deranged hormones cause the womb lining to be out of sync with the embryo.

A Beneficial Add-on

The EmbryoGlue is known to be an add-on that helps increase the chances of pregnancy. So, what is the composition of the EmbryoGlue and how does it work?

  • It is not an actual glue, but it acts like glue by increasing the chances of implantation of the embryo to the womb.
  • It is an implantation promoting transfer medium that consists of a high concentration of hyaluronan and recombinant human albumin, both of which promote implantation.
  • It is uniquely developed to mimic the conditions in the female uterus in order to help embryos implant after an embryo transfer.
  • Before the embryo transfer is to take place, the embryos are taken out from the incubator and placed in a medium enriched with EmbryoGlue for a duration of between 30 minutes to 3 hours. This is to bind the substance to the embryos.
  • The EmbryoGlue causes the embryo transfer medium to thicken, becoming more similar to the uterine fluids. The thickening of the medium improves its ability to mix with the uterine fluids which helps to prevent the embryo from drifting.
  • The EmbryoGlue acts as an adhesive for the embryo as it implants itself in the wall of the womb.
  • The EmbryoGlue seems to be highly beneficial for women above the maternal age of 42 and with a history of implantation failures after IVF.

Seeing some increase in pregnancy rates with the usage of EmbryoGlue, Dr. Navdeep has chosen to use the EmbryoGlue consistently for all of his IVF cases in his center regardless of patients’ age and history. It is his part in doing whatever it takes to help couples realise their dream of conceiving that child so wished for.

Costing only about a few hundred ringgit, the EmbryoGlue is quite affordable and worth using considering its benefits. 

Since the EmbryoGlue’s medium conditions are quite similar to that of the uterine fluids, there has been no known risks to the embryo or the patient from its usage.

Getting It Right at the First Attempt

Going through the whole IVF journey can be physically and emotionally challenging for a couple; it is really no walk in the park. With this in mind, Dr. Navdeep believes in doing everything possible to get it right the first time an IVF procedure is carried out. Weighing its benefits, couples undergoing IVF can rest assured that adding on the EmbryoGlue during the embryo transfer stage helps in enhancing implantation. Although this does not guarantee a pregnancy, it certainly helps to increase the chances of a couple hearing, "You're pregnant", words they have been so eagerly awaiting to hear. 

You are sure to have many questions. In addressing infertility, the sooner you have them answered, the better. Do list them down and call 03-8069 9333 (TMC Fertility & Women’s Specialist Centre, Puchong) or 03-62871000 (Thomson Hospital, Kota Damansara) or email ask@drnavdeepfertility.com to make an appointment to consult with Dr Navdeep.

IVF Technology

IVF Technology: Time-lapse Incubator

An Up-Close and Personal View of the Secret Life of Embryos

“I want to do everything possible within my control to ensure that

every step of the IVF process is done right.” 

-Dr Navdeep Singh Pannu-

Every process counts

When a couple is faced with the option of in vitro fertilisation (IVF), it is likely that all other significant measures to conceive have failed. In such an instance, I want to do everything possible within my control to ensure that every step of the IVF process is done right.

Time-lapse Incubator

 The Time-lapse Incubator is a less talked about advancement in IVF but to me personally, the value of this technology is immense as it is obvious. To understand its role, it is important to know where in the IVF process the Time-lapse Incubator lends its pertinence.

During IVF, mature eggs are retrieved from ovaries and fertilised outside the uterus. The fertilised eggs, now embryos, are placed in a substance that supports their growth. The embryos are subsequently placed in an incubator under a carefully controlled environment.

At regular intervals, the incubator is opened and an embryologist monitors the embryos’ morphology. He or she checks the number of cells and if they are dividing appropriately as well as monitors other significant markers. However, there is a predicament.

On the one hand, we want to observe as much as possible the developing embryos to be able to select the best to transfer or deselect those with a lower implantation potential. On the other hand, each time the incubator is opened, the highly controlled environment the embryo is in is disturbed.  This is a conundrum that the time-lapse technology effectively addresses.

Observing safely to increase selection success

The use of time-lapse technology in an IVF lab allows embryos to remain in the incubator while a camera continuously takes images of their development. The images are put together into a film and the embryos can now be consistently observed minus the stress of handling.

Time-lapse technology enables the documenting of events which may otherwise be missed in traditional observation such as the dynamic morphology of embryo development, its patterns and morphokinetics. These events tell us a lot about the developmental potential of an embryo.

The information gained from using time-lapse technology guides us in selecting embryos that are developing normally and in determining the optimum time for transfer within the five-day observation period, thus increasing the chances of a successful pregnancy.

Strides for better IVF success rates

The success of an IVF procedure is never guaranteed, as with any other Assisted Reproductive Technology (ART) interventions. However, the IVF process is made up of several procedures and experience has shown me that the compounded success of each process positively contributes to eventual success.

The Time-Lapse Incubator is part of the IVF process that I prescribe for patients under my care and it has been instrumental in empowering decisions that have brought couples closer to their hope of building a family.

You are sure to have many questions. In addressing infertility, the sooner you have them answered, the better. Do list them down and call +6-03-80699333 (TMC Fertility & Women’s Specialist Centre, Puchong) or +6-03-62871000 (Thomson Hospital, Kota Damansara) or email ask@drnavdeepfertility.com to make an appointment to consult with Dr Navdeep.